DOSE-EFFECT RELATIONSHIP OF DIFFERENT ACUPUNCTURE COURSES ON CHRONIC INSOMNIA DISORDER: STUDY PROTOCOL FOR A RANDOMIZED CONTROLLED TRIAL

Dose-effect relationship of different acupuncture courses on chronic insomnia disorder: study protocol for a randomized controlled trial

BackgroundChronic insomnia disorder (CID) is increasing in prevalence year by year, is long lasting, and potentially risky.Acupuncture has been widely used in the clinical management of this condition.However, there is still a lack of direct evidence on the dose-effect relationship between different acupuncture courses and clinical efficacy.To iden

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Development of High Cell Density Cultivation Strategies for Improved Medium Chain Length Polyhydroxyalkanoate Productivity Using Pseudomonas putida LS46

High cell density (HCD) fed-batch cultures are widely perceived as a requisite for high-productivity polyhydroxyalkanoate (PHA) cultivation processes.In this work, a reactive pulse feed strategy (based on real-time CO2 or dissolved oxygen (DO) measurements as feedback variables) was used to control an oxygen-limited fed-batch process for improved p

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Use of zebrafish to study Shigella infection

Shigella is a leading cause of dysentery worldwide, responsible for up to 165 million cases of shigellosis each year.Shigella is also recognised as an exceptional model pathogen to study key issues in cell biology and innate immunity.Several infection models have been useful to explore Shigella biology; however, we still lack information regarding

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Case Report: First Evidence of a Benign Bone Cyst in an Adult Teckel Dog Treated With Shark Teeth-Derived Bioapatites

Bone cysts are a very rare orthopedic pathology in veterinary medicine, the general prevalence of which is unknown.A unicameral bone cyst was diagnosed in an adult female Teckel dog with a limp that was treated surgically by filling campicon.com the defect with marine bioapatites.The treatment was effective and at 8 weeks the defect had remodeled 5

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